According to the new research that the Queen’s University in Canada studied, melanoma can be reduced when MicroRNA 193b is added in the skin. MicroRNA 193b is a gene that can be found in the DNA of all humans.

Melanoma is uncontrollable tumor of producing melanin cells in the skin. In addition to this, the newly found miR-193b is classified as small genetic molecules that modulate the expression of gene.

The pathology head and molecular medicine Victor Tron said that miR-193b can help in lowering the risk of having melanoma cancers. Although this gene is unknown for the last ten years, scientists keep looking for this gene to help people who have melanoma. Dr. Tron and his colleagues experiment this gene that might have significance in any science discovery but it turns out to be an important factor in slowing down melanoma.

In their experiments, they added miR-193b in the cells of melanoma and the result lowered the levels of cyclin D1 and reduced the growth of melanoma cells. Through the experiments done in their laboratory, tissue samples confirmed that the miR-193b plays a significant role in the process of melanoma. However, more research is needed to know exactly why the levels of miR-193b go up and down.
Dr. Tron also added that this discovery needs a lot more studies to do about curing melanoma. It is the most particular type of cancer in the skin. According to its percentage, 75 percent of the people with melanoma died because of this disease.

Taking Zometa or the drug used to medicate and strengthen the bone can be a lot of help to fight the metastatic breast cancer before the surgery.

It is the complexity of the breast cancer wherein the cancerous cells are already spreading in the other parts of the body. According to the University School of Medicine in St. Louis, patients that are taking this kind of drug three months ahead before the surgery for breast cancer will do a good medication because it can lower the number of tumor cells in the bone marrow.

Disseminated Tumor Cells (DTCs) are tumors that scatter everyday with thousands of tumor cells in the body.  The DTCs of breast cancer are sometimes associated in the bone marrow when the growth of the bone helps them to survive.

Patients that undergo chemotherapy can expand the turnover of the bone and the growth factors of it. It is possible to intensify the problem of disseminated tumor cells in the bone, which can cause the patients to have a metastatic illness in breast cancer.

The DTCs sanctuary is the bone marrow itself. It allows them to scatter and circulate in the different body organs that can lead to patient’s sudden death. According to Dr. Rebecca Aft, a professor and specialist in cancer of the breast in Alvin J. Siteman Cancer Center and in the Medical School in Washington University believed that Zometa suppress the growing factors to help support the expansion of DTCs.

Zometa also known as zoledronic acid is advised to lower and stop the complications in the bone because of many bone metastases and myeloma that comes from solid tumors. In addition to this, two researches have shown that Zometa helps the free survival of the disease when taken along with estrogen-lowering therapy before the surgery in the breast cancer.

The results of these studies are proven to improve and help the patient’s condition to reduce the tumor cells and to stop the spreading of the tumor cells in the other parts of the body.

A new study finds that stem cells can be used to treat heart attacks and cardiomyopathy.
According to Professor Michael Schneider, British Heart Foundation Professor at Imperial College London, the use of stem cells in clinical trials to treat heart damage is very successful when it comes to safety but the bone marrow stem cells only gives a small improvement in how well the heart is pumping.
Schneider said that they are want to use stem cells to improve the heart beat of their patients but these kind of cells are not found in the bone marrow. He also stated good news that they are already finding ways to identify and purify these cells that can be a big help for their study.
According to reports, almost 1000 patients have been successfully treated in 20 clinical trials worldwide. Bone marrow stem cells are used to repair the damage caused by heart attacks and diseases. Schneider said that there is a significant way to produce beating heart cells from stem cells. Using embryonic stem cells like induced pluripotent cells and heart-derived stem cells are the best proven approaches to create new beating heart cells.
Schneider added that using heart-derived stem cells is safer than using embryonic and induced pluripotent cells in treating cardiomyopathy and heart attack. He also said that of all the cell types, only heart-derived cells are used in human clinical trials for these kinds of treatments. According to Schneider, the biggest challenge will be the development of an ideal product which will be either a pure population of some kind of precursor or a mixture of blood-vessel forming cells and heart-muscle forming cells.
According to the scientists, the next stage of this study is to develop this technique into a method of purifying, extracting and multiplying heart stem cells to repair the damage caused by heart attacks and cardiomyopathy.

A study found out that almost 250,000 children fight as soldiers in 86 countries around the globe and they found out how these children adjust when they come home.

There are two new studies explored on how the children from war adapt to their environment when they return home. They found out that the key to successful adaptation is one of the characteristics of the communities where they returned to.

According to the first study conducted, the former child soldiers from Sierra Leone who live in communities where they are fully accepted have less depression and they are more confident to interact with other people. They also showed positive behaviors and attitudes when they are in school. However, these situations cannot be compared to the trauma that they felt when they are in the battlefield.

The second study shows that children who returned to less violent homes and communities adapted the best. These children did not develop survivor guilt and seek revenge for what happen. They have better socioeconomic situations and perceived spiritual support.

These studies appeared in the July/August issue of the journal Child Development. It is posted in the special section on children and disaster.
According to the researchers, the children are exposed in a high level of violence when they are in the battlefield like massacres and village raids. More than one third of the girls are raped and almost a quarter of both girls and boys are injured according to the report.

According to Theresa Betancourt, assistant professor of child health and human rights at Harvard School of Public Health, witnessing a general violence will not have a strong effect on the psychological and social adjustment of the children who experienced it but the children who killed someone or children that experienced rape will have a really hard time in adjusting in their environment.

Researchers found a new model for the development and progression of an incurable blood cancer, multiple myeloma.
According to the researchers, multiple myeloma is one of the most common blood cancers and it is considered to be incurable. They found a conceptually new model for the progression of the deadly blood cancer. This study brings a new hope for the treatment of the disease. This study was done and published in the online journal PLos ONE in the July edition.
The researchers identified a group of genes that are silenced by the epigenetic mechanisms inside the malignant plasma cell. They used a large group of patients with myeloma to study their cells. According to Helene Jernberg Wiklund, one of the investigators in the study and the professor at the Department of Genetics and Pathology in Uppsala University, the silencing of the genes may lead to the uncontrolled growth of the malignant plasma cells.
The researchers compared the silenced gene profiles to the normal plasma cells. These normal cells are highly specialized and it is where growth and lifetime is controlled. The researchers found out that the silenced genes have a common denominator. They are targeted and controlled by the Polycomb repressor complex (PcG). It has been associated in division and self-renewal of normal embryonic cells. The researchers found that the inhibitors of PcG can also decrease the growth of the tumor cells in an animal model of myeloma.
According to the researchers, they are still not sure if the inhibitors of PcG can really decrease the growth of myeloma tumor cells on humans but they are still studying if it is possible. They also said that with this study, there will be a new hope for people with myeloma.
According to Wiklund, their strategy is to develop drugs that can treat myeloma. They will target the PcG complex to reactivate the silenced gene profile.

According to the new study, men and women that are suffering from osteoarthritis can now go with the activities that they really want to do with the new therapy for them.

Dr. Brian Feeley, an instructor at University of California in San Francisco, said that the percentage of person that knee arthritis is increasing. People with the age of 40 to 60 are the most targeted age of having knee arthritis.

Feeley also added that in order to prevent knee arthritis, they must select an appropriate therapy for them. However, non-surgical and surgical treatments are for younger patients only.

Elderly patients in the other hand expect to have more serious treatment in order for them to stay active as younger age do.
Dr. Feeley said that people at the age of 40 and up do not want to stop their activities and even their sports. That is why doctors and orthopedic surgeon are looking for different therapy that can help those patients to stay active with their lifestyle even they are suffering from knee arthritis.

According to Dr. Feeley, operation is only advisable to those who have serious signs of knee arthritis. However, it is not recommendable with patients that are doing well even with their illness. Although there are other option like glucosamine, chondroitin and acupuncture in treating knee arthritis, there is still no proof that this can replace the needed treatment for patients.

Feeley also added that serious cases of knee arthritis must undergo surgery, however, right treatment and physical therapy is still needed that can help patients to feel better and more active.

According to the new study that is conducted by epidemiologist in University of Buffalo, pregnant women who are exposed in the environment of air pollution does not raise the possibility of having a preeclampsia, a condition that rises with pregnant women due to hypertension.
This study survey almost 3, 675 pregnant women in Seattle Washington to analyze the effects of pregnant women’s surroundings and their health diet during pregnancies. According to Carole Rudra, PHD, an assistant and instructor in the University of Buffalo said that the result of this study is shown in the yearly meeting of Society for Pediatric and Perinatal Epidemiology.
Rudra researches for the factors that may affect the behavioral stability of pregnant women towards their environment. Rudra also added that air pollutants may raise the possibility of having disease in cardiovascular that lead Rudra to research for some factors that air pollution may also be a of having preeclampsia.
Rudra together with other co-workers gather some data from pregnant women that are exposed in some air pollutant like air borne particles like mist, dust and so alike and with carbon monoxide (CO). According to the data, those pregnant women that are exposed in this kind of air pollutant do not show any signs that these air pollutants really affects the pregnancies of women.
They began their studies in finding answer if the pollutants in air can cause preeclampsia. However, the researcher found out that air pollution is not connected with the danger of having preeclampsia in pregnant women.
In addition to this, Rudra wants to continue this research in analyzing and examining the health of these pregnant women that may affect the risk of preeclampsia.

According to the report in the health issue for July, disorder in anxiety can be a higher risk with patients that already have heart diseases. Moreover, this kind of disorder is also a factor of having heart failure, heart attack, stroke and death.

In addition to this, patients that are suffering from heart disease also have signs of anxiety disorder and the percentage of these patients is almost 24 percent to 31 percent. The author of the study also said that patients that have heart disease and anxiety are really connected.

Many of the studies have proven that the signs of anxiety disorder are prognostic of impairment that may also increase the possibility of having low quality in life for those patients that have heart disease. However, there are still some unproven data that can link anxiety from increasing the risk of having heart disease.

Dr. Elisabeth J. Martens of University of Tilburg in Netherlands surveyed 1, 015 patients that already have heart disease. According to the data, they analyzed the result of their urine and blood samples. Moreover, they also use the data gathered from testing their exercising ability and done electrocardiography.

Through the Diagnostic Interview Schedule, they examined the presence of depressive disorder and anxiety disorder that are link to heart disease.

With the survey done with 106 patients having heart disease, they conclude that there are high risk of anxiety with heart disease for about 9.6 percent and there are about 6.6 percent of patients are not having anxiety disorder. After deep evaluation of this study, the percentage shows that it is about 74 percent that is connected in cardiovascular diseases and anxiety.

According to a study in the Journal of the American Society and Nephrology, people having low beat-to-beat heart rate variability and high resting heart rate may have an increase risk of developing kidney diseases.

According to the research, the behavior of the autonomic nervous system can be a marker to determine late development of kidney diseases. The autonomic nervous system regulates the body functions like responses to stress, temperature regulation, heart rate, and blood pressure. The dysfunction in the autonomic nervous system is associated with chronic kidney diseases but the relationship is not yet clear. They need to conduct more research regarding this study.

According to Daniel Brotman, MD (Johns Hopkins University School of Medicine), the study of the relationship between subsequent development of kidney disease and dysautonomia is very important in the discovering new therapies for kidney diseases. They studied 13,241 people who participated in the Atherosclerosis Risk in Communities (ARIC). To assess dysautonomia, they measure the heart rate variability of the subjects.

According to the researchers, the resting heart rate of young adults accelerates and decelerates as they breathe.  Lower resting heart rates and higher beat-to-beat variability in heart rate indicates a healthy autonomic nervous system and normal cardiovascular health. It only means that higher resting rates and lower beat-to-beat variability indicates dysautonomia.

Dr. Brotman found out that people with higher resting rates have higher risk in developing kidney failures. They concluded that heart rate measurements can be a way to know if a patient can have higher risk of kidney diseases.

According to Dr. Brotman, the study does not show cause and effect. They have no solid proof about the relationship of heart rate and kidney diseases. They are hoping that their study will encourage further research in this study to find new therapeutic approaches for kidney diseases.

According to the research in California, patients that are suffering from hypertension and diabetes and frequently communicating with their physicians have seen more improvements with their health.

Since patients are communicating with their physicians more often, their doctor always has a chance to check their blood pressure and their blood sugar through emails. This is implemented by Kaiser Permanente health system in year 2004 as a part of nation wide campaign for this process of having communication with the patients and their physicians through emails.

There are almost three million people with the same diseases stated above signed this campaign and before the year 2008 end, there are 3, 092 physicians and 35, 423 patients that are already using it for their own privilege.

In addition to this, there are already 630, 807 emails that are sent and delivered between physicians and patients from March 2006 up to December 2008. Moreover, it also reaches for almost 85 percent now who are using this kind of method.
The progress of this method has the percentage of 2.4 percent to 6.5 percent in controlling blood sugar and has screening for it. Moreover, patients who have emailed their physicians can screen and control their cholesterol for those who have disease in kidney.

Furthermore, those who are emailing their physicians that are suffering from hypertension or diabetes always have a level of 140/90 of their blood pressure rather than those who have not.
Aside from the fact that the physicians can monitor their patient’s health through emails, the improvements are also in higher achievements. Since patients are able to tell their doctors about what they are feeling for that very moment can help them feel good and no need to worry.

According to Terhilda Garrido, the author of this study said that through this method, most of their patients tend to be close with their physicians and their relationship as doctor-patient and patient-doctor really improve together with the improvement of their patient’s health.